Generic Name: finasteride, dosage Form: tablet, film coated, show On This Page, propecia and low testosterone view All. Show On This Page, indications and Usage for Propecia, propecia is indicated for the treatment of male pattern hair loss (androgenetic alopecia) in MEN only. Efficacy in bitemporal recession has not been established. Propecia is not indicated for use in women. Propecia Dosage and Administration. Propecia may be administered with or without meals. The recommended dose of Propecia is one tablet (1 mg) taken once daily. In general, daily use for three months or more is necessary before benefit is observed. Continued use is recommended to sustain benefit, which should propecia and low testosterone be re-evaluated periodically. Withdrawal of treatment leads to reversal of effect within 12 months. Dosage Forms and Strengths, propecia tablets (1 mg) are tan, octagonal, film-coated convex tablets with "stylized P" logo on one side and Propecia on the other. Contraindications, propecia is contraindicated in the following: Pregnancy. Finasteride use is contraindicated in women when they are or may potentially be pregnant. Because of the ability of Type II 5-reductase inhibitors to inhibit the conversion of testosterone to 5-dihydrotestosterone (DHT finasteride may cause abnormalities of the external genitalia propecia and low testosterone of a male fetus of a pregnant woman who receives finasteride. If this drug is used during pregnancy, or if pregnancy occurs while taking this drug, the pregnant woman should be apprised of the potential hazard to the male fetus. Warnings and Precautions (5.1), Use in Specific Populations (8.1), How Supplied/Storage and Handling (16) and, patient Counseling Information (17.1). In female rats, low doses of finasteride administered during pregnancy have produced abnormalities of the external genitalia in male offspring. Hypersensitivity to any component of this medication. Warnings and Precautions, exposure of Women Risk to Male Fetus. Women should not handle crushed or broken Propecia tablets when they are pregnant or may potentially be pregnant because of the possibility of absorption of finasteride and the subsequent potential risk to a male fetus. Propecia tablets are coated and will prevent contact with the active ingredient during normal handling, provided that the tablets have not been broken or crushed. Indications and Usage (1), Contraindications (4), Use in Specific Populations (8.1), How Supplied/Storage and Handling (16) and, patient Counseling Information (17.1). Effects on Prostate Specific Antigen (PSA). In clinical studies with Propecia (finasteride, 1 mg) in men 18-41 years of age, the mean value of serum prostate specific antigen (PSA) decreased from.7 ng/mL at baseline.5 ng/mL at Month. Further, in clinical studies with proscar (finasteride, 5 mg) when used in older men who have benign prostatic hyperplasia (BPH PSA levels are decreased by approximately. Other studies with proscar showed it may also cause decreases in serum PSA in the presence of prostate cancer. These findings should be taken into account for proper interpretation of serum PSA when evaluating men treated with finasteride. Any confirmed increase from the lowest PSA value while on Propecia may signal the presence of prostate cancer and should be evaluated, even if PSA levels are still within the normal range for men not taking a 5-reductase inhibitor. Non-compliance propecia and low testosterone to therapy with Propecia may also affect PSA test results. Increased Risk of High-Grade Prostate Cancer with 5-Reductase Inhibitors. Men aged 55 and over with a normal digital rectal examination and PSA.0 ng/mL at baseline taking finasteride 5 mg/day (5 times the dose of Propecia) in the 7-year Prostate Cancer Prevention Trial propecia and low testosterone (pcpt) had an increased risk of Gleason score 8-10 prostate cancer.
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